Wednesday, October 15, 2014

Rapid and durable protection against Ebola virus with new vaccine regimens

The article describes a new experimental vaccine that was injected into macaque monkeys. The article stated that the vaccine inoculation protected the monkeys initially but lost some of its protection after a time. The vaccine seemed to work better when it was given to the monkeys as a booster ten months after the initial inoculation. This  booster inoculation also appears to work better when an additional vaccine was given.
 
This article is very significance given the dangers that the ebola virus can create to mankind. The research being done by the National Institute of Allergy and Infectious Diseases and The US Army Medical Research Institute and Okairos a biotechnical company is focusing on a very serious health issue in the world. This collaboration of many experts is doing the research that may lead to a cure or protection against the ebola virus.
 
It seems that the research discussed in this article is based on good scientific practice but there wasn’t enough reproduction of the test.The article states that the vaccine was only given to four monkeys and although the results are promising there needs to be more research. The other thing is that the vaccine appears to be successful on monkeys but this may not be reproduced in human.

8 comments:

  1. This review written by Naoko Mitsui about the Ebola virus was an informative but brief review. I chose this review to comment on because of how terrifying Ebola is, and how it is striking fear into the hearts of Americans, and people all around the world. One aspect I liked about the review is the topic Naoko picked, as this is the biggest health issue in our world right now. Another component that was impressive was her review, stating that although the vaccine appears to be successful, there needs to be more reproduction of the test before it can be used as a treatment for humans. One last element I enjoyed is that Naoko gave a good description of the testing that was done on the macaque monkeys, that it seemed to work better as a booster ten months after the initial inoculation. One aspect I would have liked to see was some background information about Ebola, as it is such an immense issue in our world today. She went too quickly right into the description of the experiment on the macaque monkeys. I also would have liked a definition of the word inoculation, which is a synonym for a vaccination. One thing that interests me is that we may be getting closer to cure to Ebola, which we need desperately for our mental sake and so victims can be saved. Overall, this was a well-done articles by Naoko Mitsui about how humans are inching closer to a cure for Ebola.

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    1. I think that the article written on ebola by Naoko Mitsui was very interesting but there were a couple things wrong with it. The thing I really liked is how she chose an article about how scientist are trying to find a cure on ebola because lately all that I’ve heard is how its spreading and getting worse and I hadn’t heard any good news. I also liked the summery paragraph because it is brief but it gives you all the information you need
      Although this is a good article there are still some things that need improvement. The first thing is that she didn’t really write a review of the article as her third paragraph is all things that should have been part of the second paragraph. Also there are some grammatical mistakes that need to be looked over. However other than those two things I think that Naoko did a nice job.
      Something that I found very interesting about this article is how it shows that people are working on a cure for Ebola. I find that relieving because lately all that’s been on the news is how Ebola is spreading and its really nice to see that people are working on a cure even though they still haven’t found one it is very reassuring.

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  2. This review written by Naoko Mitsui was very interesting but lacked of a little bit of detail. Naoko did a good job explaining how the vaccine was used on the monkeys and how it later started to wear off from their bodies. This was very informative and it showed that scientists and health professionals will hopefully find a way to solve this problem and allow the vaccine to stay in our bodies forever. Furthermore, I like how in her article she used information from the Allergy and Infectious Diseases Institute, The US Army Medical Research Institute and Okairos. I was able to learn something new from professionals and experiments which I know must have valid and trustworthy results/research. Lastly, I liked not only the article she chose but also the way that she talked about how the vaccines may only work on monkeys. Naoko states that "this vaccine appears to be successful on monkeys but this may not be reproduced for humans". Scientists will have to do further experiments in order to make the vaccine applicable for humans. Even though this article talked about the important facts in the article I found it a little vague. Naoko could have gone a little bit more in depth in the vaccines like what was in it, why was it tested on monkeys... She could have done a little bit of outside research even if it wasn't in the article so her review could have more detail. As well as outside research, she could have added quotes from experts during this experiment to tell the reader what researches are thinking about this Ebola outbreak and how to solve it. A second thing that she should watch out for are some of her spelling and gramatical errors. Even though there weren't that many, it could have made the article flow more smoothly. Something that stood out to me while reading this review, was how quick ebola was spreading throughout the country as well as the world. The more research scientists due, the closer we will be to finding a cure. We are almost there! In conclusion, I thought that Naoko's review was good overall. It was informative although vague but I definitely learned something from it.

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  3. This article review by Naoko Matsui was very interesting and provided information about Ebola. I thought that review provided a good summary, and told the readers good information. She did a good job on explaining what worked on the vaccine and what didn’t work. A third aspect of the article that Naoko did well was that she added great comments on what the author of the original article could have added. I think Naoko could have included some more information on the information of Ebola, as many don’t know exactly what the disease of Ebola does to the body (including me). She also could have used simpler words for readers of our age, for example I didn’t know what the word inoculation meant. I learned a lot from this article review however, one thing that I didn’t know was that Ebola can affect animals, and it was a questioned I had wondered for a couple weeks already. I thought this article review was very informational but lacked some detail and could have been improved easily.

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  4. In this article, Rapid and durable protection against Ebola virus with new vaccine regimens, the author explains a new vaccine that was tested on macaque monkeys. Naoko Mitsui did a very well job reviewing this article. However at parts she didn't include information that would have been necessary. Naoko provided the test results information, when the vaccine worked better when it was given 10 months after the inoculation. Naoko also gave research information from the National Institute of Allergy, Infectious Diseases, the US Army Medical Research Institute and Okairos, saying that its a serious health issue and they are hoping to find a cure soon. A third thing I thought Naoko did well was she wrote an article that has a huge impact on us today. Two things Naoko could have touched upon was more detail. the actual it self was packed with information and she left it with no information. She also didn't talk say why it was tested on macaque monkeys. One aspect I found interesting was how fast they are working to find a cure even though it had only spread to a couple people in the United States. Although its a horrible virus and they should work on it, its surprising how fast people are reacting to this. Overall I think Naoko did a very good job reviewing, Rapid and durable protection against Ebola virus with new vaccine regimens.

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  5. Naoko’s review of “Rapid and Durable Protection against Ebola Virus with New Vaccine Regimens” was well written. Naoko wrote a very good opening sentence that made me want to read her review. Her opening sentence was “The article describes a new experimental vaccine that was injected into macaque monkeys.” Her opening sentence created many questions in my mind such as “What are macaque monkeys?” and “What does this experimental vaccine do?” Naoko also gave a good summary of the main idea of the article. She explained that this experimental vaccine protected the macaque monkeys at first, but then the vaccine lost some of its effectiveness over time. Naoko also did a great job stating her article’s significance to humanity. She stated that Ebola is a very serious issue in the world, and that the collaboration of many experts doing research against the virus might lead to a cure! This is very encouraging because coverage about the danger of the Ebola virus is all over the news, and many people are concerned about it.
    Although her review was well written, I thought that Naoko could have done a few things better. She could have reread her write-up before she submitted it to find any errors. There were a few typos. I also wish that Naoko had answered more of the questions I had after reading the first sentence of her review. In her review, she did not say what macaque monkeys are and why they were used to experiment with the vaccine. She also did not say how the experimental vaccine first protected the monkeys from the Ebola virus and why scientists concluded that the vaccine eventually lost some of its effectiveness.
    Naoko picked a great topic that immediately grabbed my interest. One thing I learned from Naoko’s review is that there is a lot of research being done by many experts around the world to figure out a cure to the Ebola virus. For example, there is research being done by the National Institute of Allergy and Infectious Diseases. There is also research being done by The US Army Medical Research Institute. Okairos, a biotechnical company, is also researching the infectious virus. With all these groups and experts working to fight against Ebola, hopefully a cure will be found soon.

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  6. I found Naoko's review of "Rapid and durable protection against Ebola virus with new vaccine regimens" very informative and well thought out. Much of Naoko's review was exceptional. I especially enjoyed how Naoko's review was brief and to the point. This made it easier for the reader to understand the important concepts in the review and get a good idea of the importance of the article. I also liked that Naoko explained the findings of the test, stating that the monkeys responded well when given a booster vaccination ten months after the first vaccination. A third aspect of Naoko's review that I liked a lot was that she gave a great discussion on the possible problems with this test. She mentioned that the test only used four monkeys, and the vaccine may not be as effective on all monkeys or humans. That being said, I thought that Naoko could do a few things better in her next review. She might have spent more time explaining what the ebola virus actually is, and explained more about how the scientists did the test. Another thing she could have done was to say what the other groups currently researching ebola were focusing on, whether it be prevention, cure, or something different. I learned that the vaccine for ebola might be approved and used to fight ebola. This review was quite interesting and centered around a topic that is very important, and Naoko did a great job of providing us an overview of the article.

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  7. The explanation of the article about the Ebola virus and new vaccine tests by Naoko Mitsui, was well written, but needed more depth. Though the first few sentences draw the reader in and make them want to continue reading. Ebola, should be explained more to let the reader know what it is, just incase they don’t know what the virus is; she should have also included how serious the issued of Ebola is. Naoko, showed what worked when using the vaccine and what unfortunately didn’t. She also included words that one may not know, which could be confusing, but I like it because it makes the review sound a little more mature. I think this article lacked some things, but overall was a very well written review.

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